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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1044998Generated: November 3, 2026

Isobutyl iodide → 6-Amino-2-(butyloxy)-9-{2-[1-(2-methylpropyl)-4-piperidinyl]ethyl}-7,9-dihydro-8H-purin-8-one

https://huagongshe.com/reaction/1044998

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsobutyl iodideHCID 10556—
Reactant2-(Butyloxy)-8-(methyloxy)-9-[2-(4-piperidinyl)ethyl]-9H-purin-6-amineHCID 58306244—
Product6-Amino-2-(butyloxy)-9-{2-[1-(2-methylpropyl)-4-piperidinyl]ethyl}-7,9-dihydro-8H-purin-8-oneHCID 67234830—

Reaction Steps

Prepared similarly to Example 80 from 2-(butyloxy)-8-(methyloxy)-9-[2-(4-piperidinyl)ethyl]-9H-purin-6-amine and 1-iodo-2-methylpropane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563717B2
Source datasetuspto-grants-2013_10
ORD IDord-e9e3c075049245f19084e85a255eff58
Source noteuspto-grants-2013_10