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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1045001Generated: November 2, 2026

Iodocyclohexane → 6-Amino-2-(butyloxy)-9-[2-(1-cyclopentyl-4-piperidinyl)ethyl]-7,9-dihydro-8H-purin-8-one

https://huagongshe.com/reaction/1045001

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIodocyclohexaneHCID 12289—
Reactant2-(Butyloxy)-8-(methyloxy)-9-[2-(4-piperidinyl)ethyl]-9H-purin-6-amineHCID 58306244—
Product6-Amino-2-(butyloxy)-9-[2-(1-cyclopentyl-4-piperidinyl)ethyl]-7,9-dihydro-8H-purin-8-oneHCID 67181243—

Reaction Steps

Prepared similarly to Example 80 from 2-(butyloxy)-8-(methyloxy)-9-[2-(4-piperidinyl)ethyl]-9H-purin-6-amine and iodocyclohexane.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08563717B2
Source datasetuspto-grants-2013_10
ORD IDord-14b8ce5f420b4da4b1df97dbd592022b
Source noteuspto-grants-2013_10