Magnesium → HCID 6931475, compound

Participants

Reaction Steps

An operation was carried out in the same manner as in Example 14, except that 0.22 mL (0.375 mmol) of 4-methoxyphenylmagnesium bromide (1.7 mol/L) prepared from magnesium and 4-methoxybenzene bromide was used instead of the anhydrous THF solution of phenylmagnesium bromide. Thus, (S)-4-methoxybenzhydrol was obtained. The conversion rate of the raw material was 98%, while the enantiomeric excess was 92% ee.

Provenance & Evidence