Tetrahydrofuran → HCID 714902, compound

Participants

Reaction Steps

An operation was carried out in the same manner as in Example 14, except that 0.375 mL (0.375 mmol) of commercial 2-thienylmagnesium bromide (1.0 mol/L) was used instead of the anhydrous THF solution of phenylmagnesium bromide. Thus, (S)-2-thienylphenylmethanol was obtained. The conversion rate of the raw material was 89%, while the enantiomeric excess was 69% ee.

Provenance & Evidence