HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfanilamide → HCID 55210129, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfanilamide | HCID 5333 | — |
| Reactant | Sodium triacetoxyborohydride | HCID 5049666 | — |
| Reactant | Tetrahydro-2H-pyran-4-carboxaldehyde | HCID 9964078 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 55210129 | HCID 55210129 | — |
Reaction Steps
4-Aminobenzenesulfonamide (6.80 g), tetrahydropyran-4-carboxaldehyde (4.96 g), and sodium triacetoxyborohydride (16.74 g) in tetrahydrofuran (300 mL) and acetic acid (15 mL) were stirred in for 24 hours. The reaction was concentrated and taken up in ethyl acetate. The resulting solution was washed with water and brine, concentrated, and chromatographed on silica gel with 50% ethyl acetate/hexanes.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08563735B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-56097c7df2294106b258f83c4a702c30 |
| Source note | uspto-grants-2013_10 |