HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1045151Generated: October 30, 2026
Chlorodifluoromethane → HCID 67422546, compound
https://huagongshe.com/reaction/1045151
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chlorodifluoromethane | HCID 6372 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Ethanamine, 2-(2-methoxyethoxy)-N,N-bis[2-(2-methoxyethoxy)ethyl]- | HCID 112414 | — |
| Reactant | 2-Fluorothiophenol | HCID 520216 | — |
| Solvent | Benzene | HCID 241 | — |
| Product | HCID 67422546 | HCID 67422546 | — |
Reaction Steps
Powdered NaOH (31.2 g), tris(2-(2-methoxyethoxy)ethyl)amine (5 mL) and 2-fluorobenzene thiol (33.6 mL) in benzene (400 mL) was saturated with chlorodifluoromethane, stirred at 80° C. for 30 minutes and filtered through diatomaceous earth (Celite®). The filtrate was washed with saturated NaHCO3 and the water layer was extracted with diethyl ether. The extracts were combined and dried (MgSO4), filtered and concentrated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08563735B2 |
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| Source dataset | uspto-grants-2013_10 |
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| ORD ID | ord-141ce723ba51471ea341a6d70fdfbea7 |
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| Source note | uspto-grants-2013_10 |
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