HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Oxan-4-yl)methanol → 5-bromo-3-fluoro-2-((4-fluorotetrahydro-2H-pyran-4-yl)methoxy)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Oxan-4-yl)methanol | HCID 2773573 | — |
| Reactant | 5-Bromo-2,3-difluoropyridine | HCID 14549654 | — |
| Reactant | 4-Fluoro-3-nitrobenzenesulfonamide | HCID 16782487 | — |
| Product | 5-bromo-3-fluoro-2-((4-fluorotetrahydro-2H-pyran-4-yl)methoxy)pyridine | HCID 67126720 | — |
Reaction Steps
The title compound was prepared by substituting EXAMPLE 306C for (tetrahydro-2H-pyran-4-yl)methanol and 5-bromo-2,3-difluoropyridine for 4-fluoro-3-nitrobenzenesulfonamide in EXAMPLE 279A.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08563735B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-8d4b232358e046c1a610ddf7fc283248 |
| Source note | uspto-grants-2013_10 |