1-Bromo-2-iodobenzene → 3-(1-Naphthyl)-1-bromobenzene
Reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1I.[C:9]1(B(O)O)[C:18]2[C:13](=[CH:14][CH:15]=[CH:16][CH:17]=2)[CH:12]=[CH:11][CH:10]=1>>[Br:1][C:2]1[CH:7]=[C:6]([C:17]2[C:18]3[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:14]=[CH:15][CH:16]=2)[CH:5]=[CH:4][CH:3]=1Participants
3
Procedure
1-(3-Bromophenyl)naphthalene was synthesized by the same method, except that in Synthetic Example 1, 2-bromoiodobenzene was used in place of 4-bromoiodobenzene and that 1-naphthaleneboronic acid was used in place of 2-naphthaleneboronic acid.
Sources & evidence
- ORD record
- ord-0c0156dae87b49899b6b77fbb34ff069
- Source dataset
- uspto-grants-2013_10
- Patent number
- US08568902B2
Reaction notes
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