HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chlorobenzylamine → 1-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-2-yl]-1H-pyrazole-4-carboxylic acid 4-chloro-benzylamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chlorobenzylamine | HCID 66036 | — |
| Reactant | (1-{9-[(4s,2r,3r,5r)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6-aminopurin-2-yl}pyrazol-4-yl)-n-(cyclopentylmethyl)carboxamide | HCID 9933850 | — |
| Product | 1-[6-Amino-9-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-2-yl]-1H-pyrazole-4-carboxylic acid 4-chloro-benzylamide | HCID 9870616 | — |
Reaction Steps
Compound 22 was prepared in a manner similar to that of compound 21 using 4-chlorobenzylamine instead of cyclopentylamine, MS 501.19 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08569260B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-611d48442aaf4e47bbce5f72cc0f9919 |
| Source note | uspto-grants-2013_10 |