反应详情

温度

0 °C

m-Toluidine (5 g, 46.64 mmol) and pyridine (3.77 mL, 46.64 mmol) were dissolved in dry dichloromethane (25 mL). To the reaction mixture, cinnamoyl chloride (7.72 g, 46.64 mmol) was added and stirred for 3 h at 0° C. The reaction mixture was extracted with dichloromethane washing with water and 2N HCl. The solvent was removed and the crude product was used in the next step without further purification.

1. extractionThe reaction mixture was extracted with dichloromethane washing with water and 2N HCl
2. customThe solvent was removed
3. customthe crude product was used in the next step without further purification