Acetic Anhydride → N'-(acetyloxy)-4-iodobenzenecarboximidamide

Participants

Reaction Steps

To a suspension of the product obtained in Step A above (8.43 g, 32.17 mmol) in 200 ml of CH2Cl2 there are added 6.72 ml (48.2 mmol) of triethylamine. 3.34 ml (35.4 mmol) of acetic anhydride are added dropwise and the solution is stirred overnight at ambient temperature. After washing 3 times with water and then with brine, the organic phase is dried over MgSO4 and evaporated. The solid obtained is taken up in isopropyl ether and then filtered to yield the title product.

Provenance & Evidence