Boron tribromide → HCID 66788781, compound

Participants

Reaction Steps

To a suspension of 29.9 g (91 mmol) of the product obtained in Step B above in 450 ml of CH2Cl2 there are added dropwise, at ambient temperature, 200 mL (200 mmol) of 1M BBr3 solution in CH2Cl2. After stirring for 30 minutes, the solution is poured onto an ice/water mixture, whilst continuing to stir. After separation and extracting once with CH2Cl2, the organic phase is washed with brine, dried over MgSO4 and evaporated. The oily residue is triturated in heptane until crystallisation takes place. The title product is collected by filtration.

Provenance & Evidence