HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Acid → 1,3-Dihydro-3,3-dimethyl-5-phenyl-2H-thieno[2,3-e]-1,4-diazepine-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | HCID 67411117 | HCID 67411117 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1,3-Dihydro-3,3-dimethyl-5-phenyl-2H-thieno[2,3-e]-1,4-diazepine-2-one | HCID 136403161 | 48% |
Reaction Steps
55 mg of the compound of Example 2 was boiled in ethanol containing acetic acid at reflux. The cyclised title compound was obtained in 48% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08569288B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-a7a8b376f38f4052bb7d44353713aaf3 |
| Source note | uspto-grants-2013_10 |