Trifluoroacetic acid → HCID 86685832, compound

Participants

Reaction Steps

The crude product from step A (801 mg, 2.033 mmol) was dissolved in anhydrous dichloromethane (4 mL). Trifluoroacetic acid (2 mL, 26 mmol) was added dropwise. Then the solution was stirred at room temperature for 3 hours. The solution was concentrated and volatiles were removed by azeotroping with toluene. The resulting crude product was purified by RP-HPLC(C18; 5% to 50% acetonitrile/water+0.05% TFA) to afford the title compound. HPLC/MS: 294.1/296.1 (M+1); 2.08 min (LC4).

Provenance & Evidence