HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → HCID 86644356, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 1H-1,2,4-Triazole | HCID 9257 | — |
| Reactant | 2,2-Dimethyl-propionic acid [(R)-2-(5-chloromethyl-7-nitro-1H-indol-2-yl)-4,5-dihydro-thiazol-4-yl]methyl ester | HCID 59542988 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Product | HCID 86644356 | HCID 86644356 | — |
Reaction Steps
2,2-Dimethyl-propionic acid [(R)-2-(5-chloromethyl-7-nitro-1H-indol-2-yl)-4,5-dihydro-thiazol-4-yl]methyl ester prepared in Preparation 41 and 1,2,4-triazole were reacted according to the same procedure as Preparation 92 except that DMF was used as the solvent instead of DMSO to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08569307B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-5863897e68e14b0fb1c0b8cfe97bdd9e |
| Source note | uspto-grants-2013_10 |