2-Bromo-4-t-butylaminocarbonylthiazole → HCID 58485386, compound

Participants

Reaction Steps

The title compound was prepared from (S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-((S)-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)-1,3-oxazinan-2-one and 2-bromo-N-tert-butylthiazole-4-carboxamide following a procedure analogous to that described in Example 1 Step 2. LC-MS Method 2 tR=1.315 min, m/z=478.3; 1H NMR (CDCl3) 1.18 (s, 3H), 1.36 (s, 3H), 1.49 (s, 9H), 2.11 (d, 3H), 2.14 (s, 4H), 2.33 (m, 1H), 2.80 (m, 1H), 5.64 (m, 1H), 7.19 (m, 2H), 7.28-7.39 (m, 5H), 7.60 (m, 2H), 7.94 (s, 1H)

Provenance & Evidence