2-Methylimidazole → HCID 49758714, compound

HRID 1046094Notes

Reaction equation

HRID 1046094 reaction equation
BrC1C=NC(Cl)=NC=1.CC1NC=CN=1.[Br:15][C:16]1[CH:17]=[N:18][C:19]([N:22]2[CH:26]=[C:25](C)[N:24]=[C:23]2[CH3:28])=[N:20][CH:21]=1>>[Br:15][C:16]1[CH:21]=[N:20][C:19]([N:22]2[CH:26]=[CH:25][N:24]=[C:23]2[CH3:28])=[N:18][CH:17]=1

Participants

4

Reactant 3

HCID 127492-MethylimidazoleHCID 6066655-Bromo-2-chloropyrimidineHCID 58485290HCID 58485290, compound

Product 1

HCID 49758714HCID 49758714, compound

Procedure

5-bromo-2-(2-methyl-1H-imidazol-1-yl)-pyrimidine was prepared 5-bromo-2-chloropyrimidine and 2-methylimidazole following a procedure analogous to that described for 5-bromo-2-(2,4-dimethyl-1H-imidazol-1-yl)-pyrimidine in Example 26.

Sources & evidence

ORD record
ord-8b4a3803d2ab44f6bb3d07b42d588685
Source dataset
uspto-grants-2013_10
Patent number
US08569292B2

Reaction notes

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