(Pyridin-4-yl)boronic acid → HCID 25181595, compound

HRID 1046106Notes

Reaction equation

HRID 1046106 reaction equation
Br[C:2]1[CH:3]=[C:4]([N:8]2[CH2:13][CH2:12][C:11]([CH3:20])([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)[O:10][C:9]2=[O:21])[CH:5]=[CH:6][CH:7]=1.[N:22]1[CH:27]=[CH:26][C:25](B(O)O)=[CH:24][CH:23]=1>>[CH3:20][C:11]1([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[O:10][C:9](=[O:21])[N:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([C:25]3[CH:26]=[CH:27][N:22]=[CH:23][CH:24]=3)[CH:3]=2)[CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 2734379(Pyridin-4-yl)boronic acidHCID 25183312HCID 25183312, compound

Product 1

HCID 25181595HCID 25181595, compound

Procedure

The title compound was prepared from 3-(3-bromophenyl)-6-methyl-6-phenyl-1,3-oxazinan-2-one and 4-pyridylboronic acid following procedures analogous to those in Example 1 Step 2. LC-MS Method 2, tR=1.329 min, m/z=345.1. 1H NMR (CDCl3) 1.70 (s, 3H), 2.30-2.50 (m, 2H), 3.30 (m, 1H), 3.50 (m, 1H), 4.10 (m, 2H), 7.27-7.50 (m, 9H), 8.60 (b, 1H).

Sources & evidence

ORD record
ord-680d55b2826e4df192c5b57ea58f9b00
Source dataset
uspto-grants-2013_10
Patent number
US08569292B2

Reaction notes

Loading…