HRID1046179

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID4192664

2-Methylpyridine-4-boronic acid

C6H8BNO2

结构：C[C@@H](c1ccc(Br)cc1)N1CC[C@](CCN2CCCS2(=O)=O)(c2ccccc2)OC1=O

HCID59635736

未命名化合物

PRODUCTS

生成物

结构：Cc1cc(-c2ccc([C@H](C)N3CC[C@@](CCN4CCCS4(=O)=O)(c4ccccc4)OC3=O)cc2)ccn1

HCID66857254

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from (S)-3-((S)-1-(4-bromophenyl)ethyl)-6-(2-(1,1-dioxo-isothiazolidin-2-yl)ethyl)-6-phenyl-1,3-oxazinan-2-one and 2-methylpyridine-4-boronic acid following a procedure analogous to that described in Example 1 Step 2.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-9f41f8964a59443ca0716e96f138c437
来源数据集: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US08569292B2
来源说明: uspto-grants-2013_10

反应 SMILES

Br[C:2]1[CH:7]=[CH:6][C:5]([C@@H:8]([N:10]2[CH2:15][CH2:14][C@:13]([CH2:22][CH2:23][N:24]3[CH2:28][CH2:27][CH2:26][S:25]3(=[O:30])=[O:29])([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[O:12][C:11]2=[O:31])[CH3:9])=[CH:4][CH:3]=1.[CH3:32][C:33]1[CH:38]=[C:37](B(O)O)[CH:36]=[CH:35][N:34]=1>>[CH3:32][C:33]1[CH:38]=[C:37]([C:2]2[CH:7]=[CH:6][C:5]([C@@H:8]([N:10]3[CH2:15][CH2:14][C@:13]([C:16]4[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=4)([CH2:22][CH2:23][N:24]4[CH2:28][CH2:27][CH2:26][S:25]4(=[O:30])=[O:29])[O:12][C:11]3=[O:31])[CH3:9])=[CH:4][CH:3]=2)[CH:36]=[CH:35][N:34]=1