N-[2-(1-Piperidinyl)ethyl]-1H-imidazole-1-carboxamide → HCID 21978262, compound

HRID 10462Notes

Reaction equation

HRID 10462 reaction equation
Cl.[NH2:2][CH2:3][CH2:4][NH:5][C:6](=[O:15])[O:7][CH2:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1.[N:16]1([CH2:22][CH2:23][NH:24][C:25](N2C=CN=C2)=[O:26])[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1>>[N:16]1([CH2:22][CH2:23][NH:24][C:25]([NH:2][CH2:3][CH2:4][NH:5][C:6](=[O:15])[O:7][CH2:8][C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][CH:14]=2)=[O:26])[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17]1

Participants

3

Reactant 2

HCID 11253042N-[2-(1-Piperidinyl)ethyl]-1H-imidazole-1-carboxamideHCID 12715871Benzyl N-(2-aminoethyl)carbamate hydrochloride

Product 1

HCID 21978262HCID 21978262, compound

Procedure

Prepared from benzyl 2-aminoethylcarbamate hydrochloride and N-[2-(1-piperidinyl)ethyl]-1H-imidazole-1-carboxamide (Preparation 18) by a similar procedure to Preparation 50. The title compound was obtained as a yellow oil.

Sources & evidence

ORD record
ord-a9cf39217da648449b967ed86fbe87b0
Source dataset
uspto-grants-2006_08
Patent number
US07094769B2

Reaction notes

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