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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1046237Generated: October 27, 2026

5-Bromo-2,4-dimethyl-1,3-thiazole → HCID 46865729, compound

https://huagongshe.com/reaction/1046237

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2,4-dimethyl-1,3-thiazoleHCID 298628—
Reactant(S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-((S)-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)-1,3-oxazinan-2-oneHCID 59532385—
ProductHCID 46865729HCID 46865729—

Reaction Steps

The title compound was prepared from (S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-[(S)-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl]-1,3-oxazinan-2-one and 5-bromo-2,4-dimethyl-thiazole following a procedure analogous to that described in Example 171. Mass spectrum (ESI+): m/z=465 [M+H]+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08569292B2
Source datasetuspto-grants-2013_10
ORD IDord-e85ab865ae1f43999a617f264c6d5725
Source noteuspto-grants-2013_10