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HRID1046247

反应详情

EQUATION

反应方程式

HRID 1046247 的结构方程式

REACTANTS

反应物

2
结构：Brc1cnc(C2CC2)nc1
HCID20444413

5-Bromo-2-cyclopropylpyrimidine

C7H7BrN2

结构：C[C@@H](c1ccc(B2OC(C)(C)C(C)(C)O2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O
HCID59532385

(S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-((S)-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl)-1,3-oxazinan-2-one

C28H38BNO5

PRODUCTS

生成物

1
结构：C[C@@H](c1ccc(-c2cnc(C3CC3)nc2)cc1)N1CC[C@](CC(C)(C)O)(c2ccccc2)OC1=O
HCID58485306

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from (S)-6-(2-hydroxy-2-methylpropyl)-6-phenyl-3-[(S)-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethyl]-1,3-oxazinan-2-one and 5-bromo-2-cyclopropyl-pyrimidine (for preparation see WO 2006004532) following a procedure analogous to that described in Example 171. Mass spectrum (ESI+): m/z=472 [M+H]+.