Hydrochloric Acid → HCID 58485292, compound

Participants

Reaction Steps

4 M aqueous NaOH solution (0.80 mL) was added to a solution of 6-(4-{(S)-1-[(S)-6-(2-hydroxy-2-methyl-propyl)-2-oxo-6-phenyl-[1,3]oxazinan-3-yl]-ethyl}-phenyl)-pyridine-2-carboxylic acid ethyl ester (0.55 g) in methanol (3 mL) and the resulting solution was stirred at room temperature overnight. Then, the solution was acidified using 1 M hydrochloric acid and the resulting mixture was extracted with ethyl acetate. The combined organic extracts were washed with brine and dried (MgSO4). The solvent was evaporated to give the title compound. Yield: 0.49 g (95% of theory); Mass spectrum (ESI−): m/z=473 [M−H]−.

Provenance & Evidence