HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 4-(bromomethyl)-3-methoxybenzoate → methyl 3-methoxy-4-[[(1S,4S)-2,5-diazabicyclo[2.2.1]hept-2-yl]methyl]benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 4-(bromomethyl)-3-methoxybenzoate | HCID 2759828 | — |
| Reactant | (1S,4S)-2-Boc-2,5-diazabicyclo[2.2.1]heptane | HCID 11521263 | — |
| Product | methyl 3-methoxy-4-[[(1S,4S)-2,5-diazabicyclo[2.2.1]hept-2-yl]methyl]benzoate | HCID 68487145 | — |
Reaction Steps
Following the above procedure, 1,1-dimethylethyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate and methyl 3-methoxy-4-(bromomethyl)benzoate are reacted together to give methyl 3-methoxy-4-[[(1S,4S)-2,5-diazabicyclo[2.2.1]hept-2-yl]methyl]benzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08569303B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-b09e844e9f124192868c71ea2be5da06 |
| Source note | uspto-grants-2013_10 |