HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 68489928, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1,1-Dimethylethyl 4-(methyl(2-(4-phenoxyphenyl)ethyl)amino)-1-piperidinecarboxylate | HCID 68489514 | — |
| Solvent | 1,1-Dichloroethane | HCID 6365 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 68489928 | HCID 68489928 | — |
Reaction Steps
A solution of 1,1-dimethylethyl 4-(methyl(2-(4-phenoxyphenyl)ethyl)amino)-1-piperidinecarboxylate (290 mg, 0.71 mmol) in dichloroethane was added a solution of hydrogen chloride in dioxane (4N). The reaction was stirred at ambient temperature for 4 hours. The reaction mixture was concentrated to dryness to give N-methyl-N-[2-(4-phenoxyphenyl)ethyl]-4-piperidinamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08569303B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-b79db03205c54c3691a34d2be0c2f5ad |
| Source note | uspto-grants-2013_10 |