Sodium Methoxide → HCID 67503079, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of tert-butyl {1-[4-(2-bromo-9H-imidazo[1,2-d]pyrido[2,3-b][1,4]benzodiazepin-3-yl)phenyl]cyclobutyl}carbamate (50 mg, 0.09 mmol) and copper iodide (1.7 mg, 0.01 mmol) in sodium methoxide solution (1 M, 5 mL) was heated at 100° C. for 24 hour. After cooling to room temperature, the precipitate was collected and purified by HPLC to give the title compound as a white solid (5 mg, 11%).

Provenance & Evidence