Cesium carbonate → HCID 59510699, compound

Participants

Reaction Steps

In a stream of argon, 73 mg of phenylboronic acid, 2.9 mg of palladium acetate, 195 mg of cesium carbonate and 12 mg of 2-dicyclohexylphosphino-2′,4′,6′-triisopropylbiphenyl were suspended in 15 mL of 1,4-dioxane. The obtained mixture was stirred at room temperature for 10 minutes. To this mixture, 149 mg of 2-[5-chloro-4′-(2-pyridyl)-1,1′-biphenyl-3-yl]-4,6-diphenyl-1,3,5-triazine, synthesized in Example 1, was added, and the resultant mixture was refluxed under heating at 110° C. for 48 hours. Then the reaction mixture was left to stand at room temperature, and was concentrated under a reduced pressure to give a solid. The solid was purified by silica gel chromatography using a hexane/chloroform mixed liquid (50:50-0:100) as a developing solvent, and then recrystallized from dichloromethane/methanol to give 153 mg of 2-{4-(2-pyridyl)-[1,1′:3′,1″]-terphenyl-5′-yl}-4,6-diphenyl-1,3,5-triazine as a white solid (yield: 95%).

Provenance & Evidence