HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Benzoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Toluene | HCID 1140 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Morpholine, 4-(1-cyclohexen-1-yl)- | HCID 69589 | — |
| Product | Benzoyl chloride | HCID 7412 | 35% |
Reaction Steps
Compound IV′c is obtained in 35% yield as a yellow powder, according to Example 4, from morpholino-enamine III′ (36.89 g, 0.17 mol, obtained in Example 2), triethylamine (24.25 g, 0.24 mol), benzoyl chloride (33.73 g, 0.24 mol), toluene (260 mL) and 20% aqueous HCl (85 mL).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08569518B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-1a2715d926314ee09adf3be5fb866369 |
| Source note | uspto-grants-2013_10 |