Benzene → N-Fmoc-L-isoleucine

Participants

Reaction Steps

0.88 (3H, t, J=6.9, —OC17H34-Me) 1.20-2.20 (75H, br, m, Alkyl-H, Ile Me-CH2—CH-Me, Pro N—CH2CH2—CH2—CH, Ala Me) 2.30 (1H, br, s, Ile Me-CH2—CH-Me) 3.38 (4H, t, J=6.6, —CH2—O—CH2—C21H43) 3.58 (1H, br, Pro CO—N—CH2—) 3.70 (1H, br, Pro CO—N—CH2—) 3.88 (2H, br, t, J=6.6, fl-O—CH2—) 4.19 (1H, t, J=6.6, fluorene (Fmoc) C9-H) 4.25-4.45 (3H, m, fluorene (Fmoc)-CH2—O, Ile or Pro or Ala α-H) 4.50 (1H, br, m, Ile or Pro or Ala α-H) 4.66 (1H, br, m, Ile or Pro or Ala α-H) 5.40 (1H, d, J=9.3, Fmoc-NH—) 6.75-7.45 (12H, m, fluorene-H or Ph-H) 7.57 (4H, br, fluorene-H or Ph-H) 7.75 (2H, d, J=7.8, fluorene-H or Ph-H)

Provenance & Evidence