Ethanol → HCID 59314334, compound

Participants

Reaction Steps

To a solution of (223) (278 mg, 0.67 mmol) and 2,2-dimethylethyleneboronic acid (134 mg, 1.34 mmol) in 10 ml EtOH is added palladium anchored homogeneous catalyst, FibreCatPd(0), (4.84% Pd, 195 mg, 0.089 mmol) and 2M aqueous solution of K2SO4 (1.78 mL, 3.56 mmol). The resulting reaction mixture is covered with argon and run in a microwave reaction: 110° C., 5 h. After concentration in vacuo, the residue is purified by HPLC to give 380 mg brown semi-solid (224).

Provenance & Evidence