HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Methyl-2-(2-methyl-1-propenyl)benzoic acid → 2-Isobutyl-3-methylbenzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Methyl-2-(2-methyl-1-propenyl)benzoic acid | HCID 59314086 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 2-Isobutyl-3-methylbenzoic acid | HCID 59314296 | 91.6% |
Reaction Steps
A solution of the 3-methyl-2-(2-methyl-1-propenyl)benzoic acid (291) (2 g, 10.5 mmol) in MeOH (40 mL) is hydrogenated using 10% palladium/carbon catalyst at 40 bar/30° C. using the Thales nanotechnology H-cube for 48 h. The MeOH is concentrated in vacuo to give the product as colorless oil (1.85 g, 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08569535B2 |
| Source dataset | uspto-grants-2013_10 |
| ORD ID | ord-679da73c132146bcb4373914592281fa |
| Source note | uspto-grants-2013_10 |