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HRID1048513

反应详情

EQUATION

反应方程式

HRID 1048513 的结构方程式

REACTANTS

反应物

2
结构：CCOC(=O)C(Br)C1CC1
HCID44222804

Ethyl bromo(cyclopropyl)acetate

C7H11BrO2

结构：C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)NC1=O
HCID58574008

未命名化合物

PRODUCTS

生成物

1
结构：C=CC[C@@]1(C)C[C@H](c2cccc(Cl)c2)[C@@H](c2ccc(Cl)cc2)N(C(C(=O)OCC)C2CC2)C1=O
HCID68000455

未命名化合物

PROCEDURE

实验过程

Coupling of (3S,5R,6S)-3-allyl-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methylpiperidin-2-one (Example 71, Step D) and ethyl 2-bromo-2-cyclopropylacetate (Example 249, Step A) using the procedure as described in Example 9, step A afforded the title compound as a mixture of two diastereomers.