HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphosgene → 1-Bromo-3-isocyanato-2-methyl-benzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphosgene | HCID 94429 | — |
| Reactant | 3-Bromo-o-toluidine | HCID 123538 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-Bromo-3-isocyanato-2-methyl-benzene | HCID 65542331 | 106.3% |
Reaction Steps
A mixture of 1-bromo-2-methyl-3-aminobenzene 25.0 g, triphosgene 60.0 g and toluene 400 mL was stirred with heating under reflux for three hours. The reaction mixtures after standing to cool were concentrated under reduced pressure to give 1-bromo-3-isocyanato-2-methylbenzene 30.3 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09380782B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-375aee307591444b8eec3f0e06405b4a |
| Source note | uspto-grants-2016_07 |