Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | HCID 86662657 | HCID 86662657 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 66778756 | HCID 66778756 | — |
Reaction Steps
To a solution of 8-(4-aminobiphenyl-3-ylamino)-8-oxooctanoate (120 mg, 0.34 mmol) in toluene was added a drop of acetic acid. The reaction was heated to 110° C. overnight and concentrated. The residue was purified by biotage column chromatography to give methyl 7-(6-phenyl-1H-benzo[d]imidazol-2-yl)heptanoate (99 mg)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US09381196B2 |
|---|
| Source dataset | uspto-grants-2016_07 |
|---|
| ORD ID | ord-048edf16fb2344398b4f0b6ef2882102 |
|---|
| Source note | uspto-grants-2016_07 |
|---|
