HRID1048683

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID962

Water

H2O

HCID5960

L-Aspartic acid

C4H7NO4

结构：CN1CCc2cccc3c2[C@H]1Cc1ccc(O)c(O)c1-3

HCID6005

Apomorphine

C17H17NO2

PRODUCTS

生成物

HCID6005

Apomorphine

C17H17NO2

结构：CN1CCc2cccc3c2[C@H]1Cc1ccc(O)c(O)c1-3.N[C@@H](CC(=O)[O-])C(=O)[O-]

HCID131735989

未命名化合物

PROCEDURE

实验过程

Apomorphine aspartate solution was prepared by dissolving apomorphine base in 0.1M aspartic acid solution. Water was added to obtain a molar ratio of 1:1, apomorphine:aspartic acid, at a final concentration of 2% apomorphine. The pH of the solution was 4.9.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e45f19d0f1a442fdbd9926dcfa5fb11c
来源数据集: uspto-grants-2016_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US09381249B2
来源说明: uspto-grants-2016_07

反应 SMILES

[CH3:1][N:2]1[C@@H:11]2[CH2:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:20])[C:14]=3[C:9]3[C:10]2=[C:5]([CH:6]=[CH:7][CH:8]=3)[CH2:4][CH2:3]1.O.[NH2:22][C@H:23]([C:28]([OH:30])=[O:29])[CH2:24][C:25]([OH:27])=[O:26]>>[CH3:1][N:2]1[C@@H:11]2[CH2:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:20])[C:14]=3[C:9]3[C:10]2=[C:5]([CH:6]=[CH:7][CH:8]=3)[CH2:4][CH2:3]1.[NH2:22][C@H:23]([C:28]([O-:30])=[O:29])[CH2:24][C:25]([O-:27])=[O:26].[CH3:1][N:2]1[C@@H:11]2[CH2:12][C:13]3[CH:18]=[CH:17][C:16]([OH:19])=[C:15]([OH:20])[C:14]=3[C:9]3[C:10]2=[C:5]([CH:6]=[CH:7][CH:8]=3)[CH2:4][CH2:3]1