4-((Tert-butoxy)carbonyl)morpholine-2-carboxylic acid → HCID 68310974, compound

HRID 1048847Notes

Reaction equation

HRID 1048847 reaction equation
C(OC([N:8]1[CH2:13][CH2:12][O:11][CH:10]([C:14]([OH:16])=O)[CH2:9]1)=O)(C)(C)C.[CH3:17][O:18][C:19]1[CH:20]=[C:21]([C@H:25]([NH2:27])[CH3:26])[CH:22]=[CH:23][CH:24]=1>>[CH3:17][O:18][C:19]1[CH:20]=[C:21]([C@H:25]([NH:27][C:14]([CH:10]2[O:11][CH2:12][CH2:13][NH:8][CH2:9]2)=[O:16])[CH3:26])[CH:22]=[CH:23][CH:24]=1

Participants

3

Reactant 2

HCID 27559654-((Tert-butoxy)carbonyl)morpholine-2-carboxylic acidHCID 7020759(R)-1-(3-Methoxyphenyl)ethylamine

Product 1

HCID 68310974HCID 68310974, compound

Procedure

The title compound was prepared by following the similar procedure as described in Step-2 of Intermediate-2 by using 4-(tert-butoxycarbonyl)morpholine-2-carboxylic acid (Step-1 of Intermediate-2) and (R)-1-(3-methoxyphenyl)ethanamine followed by deprotection of resultant Boc protected compound by following the similar procedure as described in Step-3 of Intermediate-2.

Sources & evidence

ORD record
ord-6eb304f6a0c24f2e9ec8cf71af8403ca
Source dataset
uspto-grants-2016_07
Patent number
US09382216B2

Reaction notes

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