(R)-1-(3-Methoxyphenyl)ethylamine → HCID 68310971, compound
Reaction equation
[CH2:1]([N:8]1[C:13](=[O:14])[CH2:12][O:11][CH2:10][CH:9]1[C:15]([OH:17])=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:18][O:19][C:20]1[CH:21]=[C:22]([C@H:26]([NH2:28])[CH3:27])[CH:23]=[CH:24][CH:25]=1>>[CH2:1]([N:8]1[C:13](=[O:14])[CH2:12][O:11][CH2:10][CH:9]1[C:15]([NH:28][C@@H:26]([C:22]1[CH:23]=[CH:24][CH:25]=[C:20]([O:19][CH3:18])[CH:21]=1)[CH3:27])=[O:17])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1Participants
3
Procedure
The title compound was prepared by following the similar procedure as described in Intermediate-7 by using 4-benzyl-5-oxomorpholine-3-carboxylic acid (Organic and Bio-Organic Chemistry (1972-1999); (1985); 2577-2580) and (R)-1-(3-methoxyphenyl) ethanamine. m/z 369.2.
Sources & evidence
- ORD record
- ord-1c80420d944f4617a04d56a92f40c5af
- Source dataset
- uspto-grants-2016_07
- Patent number
- US09382216B2
Reaction notes
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