Thionyl Chloride → HCID 117676168, compound

HRID 1049064Notes

Reaction equation

HRID 1049064 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:11](=[O:18])[C:10]([C:19]([OH:21])=O)=[CH:9]2)=[CH:4][CH:3]=1.O=S(Cl)[Cl:24]>>[F:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:17]3[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=3)[C:11](=[O:18])[C:10]([C:19]([Cl:24])=[O:21])=[CH:9]2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 24386Thionyl ChlorideHCID 15077916HCID 15077916, compound

Product 1

HCID 117676168HCID 117676168, compoundYield 95.1%

Procedure

A mixture of intermediate k 2 g (0.007 moL) and sulfoxide chloride (20 mL) was heated to reflux for 6 h, the excess sulfoxide chloride was evaporated in vacuo to obtain white solid 2 g. Yield: 95.1%.

Workup

  1. temperaturewas heated
  2. temperatureto reflux for 6 h
  3. customthe excess sulfoxide chloride was evaporated in vacuo

Sources & evidence

ORD record
ord-8c359a6beeab4377be1a76e0fb83fdd8
Source dataset
uspto-grants-2016_07
Patent number
US09382232B2

Reaction notes

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