Hydrazine → HCID 4164367, compound

HRID 1049156Notes

Reaction equation

HRID 1049156 reaction equation
CS[C:3]([NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[C:4]([C:7]#[N:8])[C:5]#[N:6].[NH2:16][NH2:17]>CCO>[NH2:6][C:5]1[NH:17][N:16]=[C:3]([NH:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[C:4]=1[C:7]#[N:8]

Participants

4

Reactant 2

HCID 9321HydrazineHCID 1704453HCID 1704453, compound

Product 1

HCID 4164367HCID 4164367, compoundYield 88.1%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of compound 6 (3.2258 g, 14.85 mmol) and hydrazine (742 mg, 23.16 mmol) in EtOH (20 mL) was refluxed for 30 min, at which time the reaction was complete as determined by TLC. The reaction mixture was poured into 100 mL ice water. The resulting precipitate was filtered and dried to give compound 7 (2.599 g, 88.1% yield, 99.8% purity) as a white powder.

Workup

  1. temperaturewas refluxed for 30 min, at which time the reaction
  2. filtrationThe resulting precipitate was filtered
  3. customdried

Sources & evidence

ORD record
ord-4d674f84d7bf4579b47f771c1c5eddeb
Source dataset
uspto-grants-2016_07
Patent number
US09382237B2

Reaction notes

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