Tributylstannane → HCID 117759815, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of ethyl 3-(3-(((2-(chloro(1-methylcyclopentyl)methyl)-2′-fluoro-5′-methoxybiphenyl-4-yl)oxy)methyl)phenyl)-3-cyclopropylpropanoate (92 mg) and 2,2-azobisbutyronitrile (3 mg) in toluene (3 mL) was added tributyltin hydride (0.13 mL), and the mixture was stirred at 100° C. for 2 hr. The solvent was evaporated under reduced pressure, and the residue was purified by silica gel column chromatography (ethyl acetate/hexane) to give the title compound (32 mg) as a colorless oil.

Provenance & Evidence