HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,3-Dimethoxybenzoyl chloride → 5-[4-(2,3-Dimethoxybenzoylamino)phenyl]1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,3-Dimethoxybenzoyl chloride | HCID 2758392 | — |
| Reactant | 5-(4-Benzoylaminophenyl)-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione | HCID 71656971 | — |
| Reactant | 5-(4-Aminophenyl)-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione | HCID 117699167 | — |
| Product | 5-[4-(2,3-Dimethoxybenzoylamino)phenyl]1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione | HCID 117699146 | 55% |
Reaction Steps
By using 5-(4-aminophenyl)-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione (100 mg, 0.315 mmol) obtained in Example 1, (3), and 2,3-dimethoxybenzoyl chloride (0.473 mmol), the title compound (83 mg, yield 55%) was obtained in the same manner as that of Example 1, (4).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09382236B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-1ec3fc64ef824563b48ad02dbc3b951d |
| Source note | uspto-grants-2016_07 |