HuagongsheHuagongshe Chemistry Print Report · For research reference only
Indole-3-Carboxylic Acid → HCID 117699477, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Indole-3-Carboxylic Acid | HCID 69867 | — |
| Reactant | 1H-Indole-3-carbonyl chloride | HCID 12380278 | — |
| Reactant | 5-(4-Aminophenyl)-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione | HCID 117699167 | — |
| Product | HCID 117699477 | HCID 117699477 | 55% |
Reaction Steps
Indole-3-carboxylic acid (51 mg, 0.316 mmol) was made into acid chloride in a conventional manner. By using 5-(4-aminophenyl)-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione (50 mg, 0.158 mmol) obtained in Example 1, (3), and indole-3-carboxylic acid chloride mentioned above, the title compound (40 mg, yield 55%) was obtained in the same manner as that of Example 1, (4).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09382236B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-0977dfc09a1d4dc5ae716582e78ffb50 |
| Source note | uspto-grants-2016_07 |