tert-Butyl (4-aminophenyl)carbamate → HCID 131732467, compound

HRID 1049719Notes

Reaction equation

HRID 1049719 reaction equation
FC(F)(F)S(O[C:7]1[CH:16]=[CH:15][C:14]2[CH2:13][CH2:12][CH2:11][CH2:10][C:9]=2[C:8]=1[N+:17]([O-:19])=[O:18])(=O)=O.[C:22]([O:26][C:27](=[O:36])[NH:28][C:29]1[CH:34]=[CH:33][C:32]([NH2:35])=[CH:31][CH:30]=1)([CH3:25])([CH3:24])[CH3:23]>>[C:22]([O:26][C:27](=[O:36])[NH:28][C:29]1[CH:30]=[CH:31][C:32]([NH:35][C:7]2[CH:16]=[CH:15][C:14]3[CH2:13][CH2:12][CH2:11][CH2:10][C:9]=3[C:8]=2[N+:17]([O-:19])=[O:18])=[CH:33][CH:34]=1)([CH3:25])([CH3:23])[CH3:24]

Participants

3

Reactant 2

HCID 688611tert-Butyl (4-aminophenyl)carbamateHCID 86689304HCID 86689304, compound2×

Product 1

HCID 131732467HCID 131732467, compoundYield 87.4%

Procedure

By using 1-nitro-5,6,7,8-tetrahydro-2-naphthyl trifluoromethanesulfonate (2.23 g, 6.86 mmol), and tert-butyl(4-aminophenyl)carbamate (1.43 g, 6.86 mmol), the title compound (2.30 g, yield 87%) was obtained as red crystals in the same manner as that of Example 1, (1).

Sources & evidence

ORD record
ord-a81e6f093eea4df1b685a33fec2e5f47
Source dataset
uspto-grants-2016_07
Patent number
US09382236B2

Reaction notes

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