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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1049780Generated: November 2, 2026

3-Methylpyridine-2-carbonyl chloride → 5-[4-[(3-Methylpyridin-2-yl)carbonylamino]phenyl]-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione

https://huagongshe.com/reaction/1049780

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Methylpyridine-2-carbonyl chlorideHCID 20487508—
Reactant1-(4-Aminophenyl)-6-ethyl-1H-benzo[b][1,4]diazepine-2,4(3H,5H)-dioneHCID 117699123—
Reactant5-(4-Aminophenyl)-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dioneHCID 117699167—
Product5-[4-[(3-Methylpyridin-2-yl)carbonylamino]phenyl]-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dioneHCID 11769913787%

Reaction Steps

By using 5-(4-aminophenyl)-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione obtained in Example 1, (3), and 3-methylpicolinic acid chloride, the title compound (yield 87%) was obtained in the same manner as that of Example 1, (4).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09382236B2
Source datasetuspto-grants-2016_07
ORD IDord-3fec1267a8224f54b675fbb6e0ce7860
Source noteuspto-grants-2016_07