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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1049793Generated: October 26, 2026

1-Naphthalenesulfonyl chloride → N-[3-(2,4-Dioxo-1,2,3,4-tetrahydronaphtho[1,2-b][1,4]diazepin-5-yl)phenyl]-1-naphthalenesulfonamide

https://huagongshe.com/reaction/1049793

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Naphthalenesulfonyl chlorideHCID 66560—
Reactant5-(3-Aminophenyl)-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dioneHCID 117699192—
ProductN-[3-(2,4-Dioxo-1,2,3,4-tetrahydronaphtho[1,2-b][1,4]diazepin-5-yl)phenyl]-1-naphthalenesulfonamideHCID 117699215100%

Reaction Steps

By using 5-(3-aminophenyl)-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione obtained in Example 53, (1), and naphthalene-1-sulfonyl chloride, the title compound (yield 100%) was obtained in the same manner as that of Example 150.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09382236B2
Source datasetuspto-grants-2016_07
ORD IDord-d7a319f1b7364bbcb372ed8b4d724205
Source noteuspto-grants-2016_07