HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Naphthalenesulfonyl chloride → HCID 117699035, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Naphthalenesulfonyl chloride | HCID 7125 | — |
| Reactant | 5-(4-Aminophenyl)-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione | HCID 117699167 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 117699035 | HCID 117699035 | 64.3% |
Reaction Steps
5-(4-Aminophenyl)-1H-naphtho[1,2-b][1,4]diazepine-2,4(3H,5H)-dione (30 mg, 0.095 mmol) obtained in Example 1, (3), and 2-naphthalenesulfonyl chloride (32 mg, 0.14 mmol) were treated by heating 11 pyridine (3 mL). A post-treatment was performed in a conventional manner to give the title compound (31 mg, yield 64%) as white amorphous.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09382236B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-e371f6529c634a6eb72434d33f997a9e |
| Source note | uspto-grants-2016_07 |