Iodoethanol → HCID 117699153, compound

HRID 1049802Notes

Reaction equation

[O:1]=[C:2]1[NH:8][C:7]2[C:9]3[C:14]([CH:15]=[CH:16][C:6]=2[N:5]([C:17]2[CH:22]=[CH:21][C:20]([NH:23][S:24]([C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=4[N+:33]([O-:35])=[O:34])(=[O:26])=[O:25])=[CH:19][CH:18]=2)[C:4](=[O:36])[CH2:3]1)=[CH:13][CH:12]=[CH:11][CH:10]=3.I[CH2:38][CH2:39][OH:40]>>[O:1]=[C:2]1[NH:8][C:7]2[C:9]3[C:14]([CH:15]=[CH:16][C:6]=2[N:5]([C:17]2[CH:22]=[CH:21][C:20]([N:23]([CH2:38][CH2:39][OH:40])[S:24]([C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][C:28]=4[N+:33]([O-:35])=[O:34])(=[O:26])=[O:25])=[CH:19][CH:18]=2)[C:4](=[O:36])[CH2:3]1)=[CH:13][CH:12]=[CH:11][CH:10]=3

Participants

Reactant 2

HCID 12225Iodoethanol

HCID 117699060HCID 117699060, compound

Product 1

HCID 117699153HCID 117699153, compound

Procedure

By using N-[4-(2,4-dioxo-1,2,3,4-tetrahydronaphtho[1,2-b][1,4]diazepin-5-yl)phenyl]-2-nitrobenzenesulfonamide obtained in Example 145, and 2-iodoethanol, the title compound was obtained in the same manner as that of Example 152.

Sources & evidence

ORD record: ord-b79dddea7ee44f7a982b12f7228dadd4
Source dataset: uspto-grants-2016_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US09382236B2

Reaction notes

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