6-amino-5-methoxy-1,3-benzothiazol-2(3H)-one → HCID 73442244, Verbindung

HRID 1049843Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1049843
Cl[C:2]1[C:3]2[C:10]([CH3:11])=[C:9]([CH2:12][CH3:13])[NH:8][C:4]=2[N:5]=[CH:6][N:7]=1.[NH2:14][C:15]1[C:24]([O:25][CH3:26])=[CH:23][C:18]2[NH:19][C:20](=[O:22])[S:21][C:17]=2[CH:16]=1>>[CH2:12]([C:9]1[NH:8][C:4]2[N:5]=[CH:6][N:7]=[C:2]([NH:14][C:15]3[C:24]([O:25][CH3:26])=[CH:23][C:18]4[NH:19][C:20](=[O:22])[S:21][C:17]=4[CH:16]=3)[C:3]=2[C:10]=1[CH3:11])[CH3:13]

Komponenten

3

Edukt 2

HCID 900149486-amino-5-methoxy-1,3-benzothiazol-2(3H)-oneHCID 900794284-Chloro-6-ethyl-5-methyl-7H-pyrrolo[2,3-d]pyrimidine

Produkt 1

HCID 73442244HCID 73442244, Verbindung

Versuchsvorschrift

25 mg (128 μmol) 4-Chloro-6-ethyl-5-methyl-7H-pyrrolo[2,3-d]pyrimidine (prepared according to intermediate example 1a) were transformed in analogy to example 1 using 6-amino-5-methoxy-1,3-benzothiazol-2(3H)-one to give after working up and purification 22.3 mg (47%) of the title compound.

Aufarbeitung

  1. customto give
  2. custompurification 22.3 mg (47%) of the title compound

Quellen und Nachweise

ORD-Eintrag
ord-7acf53889eb8416db4dce396a69ece4a
Quelldatensatz
uspto-grants-2016_07
Patentnummer
US09382255B2

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