Isobutyl ketone → HCID 178443511, compound

HRID 1049848Notes

Reaction equation

HRID 1049848 reaction equation
[NH:1]([C:3]1[N:8]=[CH:7][N:6]=[C:5]([OH:9])[CH:4]=1)[NH2:2].[CH3:10][CH:11]([CH2:13][C:14](=O)[CH2:15][CH:16]([CH3:18])[CH3:17])[CH3:12]>>[CH3:10][CH:11]([CH2:13][C:14](=[N:2][NH:1][C:3]1[N:8]=[CH:7][N:6]=[C:5]([OH:9])[CH:4]=1)[CH2:15][CH:16]([CH3:18])[CH3:17])[CH3:12]

Participants

3

Reactant 2

HCID 7958Isobutyl ketoneHCID 178514311HCID 178514311, compound

Product 1

HCID 178443511HCID 178443511, compound

Procedure

10.00 g (79.3 mmol) 6-hydrazinopyrimidin-4-ol (CAS-No: 29939-37-5) were transformed in analogy to intermediate example 1c using 2,6-dimethylheptan-4-one to give after working up and purification 8.77 g (44%) of the title compound.

Workup

  1. customto give
  2. custompurification 8.77 g (44%) of the title compound

Sources & evidence

ORD record
ord-47d66a666b014fb79ea0bf1a09bb6131
Source dataset
uspto-grants-2016_07
Patent number
US09382255B2

Reaction notes

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