HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate → Ethyl 4-[(5-methoxy-2-oxo-2,3-dihydro-1,3-benzothiazol-6-yl)amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate | HCID 21262606 | — |
| Reactant | 6-amino-5-methoxy-1,3-benzothiazol-2(3H)-one | HCID 90014948 | — |
| Product | Ethyl 4-[(5-methoxy-2-oxo-2,3-dihydro-1,3-benzothiazol-6-yl)amino]-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate | HCID 73442308 | — |
Reaction Steps
75 mg (332 μmol) ethyl 4-chloro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylate (CAS-No: 187725-00-4) were transformed in analogy to example 1 using 6-amino-5-methoxy-1,3-benzothiazol-2(3H)-one to give after working up and purification 20.0 mg (15%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09382255B2 |
| Source dataset | uspto-grants-2016_07 |
| ORD ID | ord-63520f616092494cb8a169fe16399d56 |
| Source note | uspto-grants-2016_07 |